Description

4-Bromo-2-hydroxypyrimidine is a halogenated heterocyclic building block of significant importance in modern synthetic chemistry. This compound serves as a versatile intermediate for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, kinase inhibitors, and other biologically active molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Serves as a versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations.
• Material Science: A precursor for the synthesis of organic ligands, dyes, and photoactive compounds.
• Academic & R&D: Employed in medicinal chemistry programs and methodological studies for heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-2-hydroxypyrimidine
CAS No.	548767-83-5
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	2-Hydroxy-4-bromopyrimidine; 4-Bromo-2(1H)-pyrimidinone; 4-Bromo-2-pyrimidinol; 4-Bromopyrimidin-2-ol; 4-Bromo-1H-pyrimidin-2-one; 2(1H)-Pyrimidinone, 4-bromo-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-hydroxypyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.