Description

n-(2-Aminoethyl)-2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetamide is a high-purity, specialized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active compounds. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of nucleoside analogs and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Bioconjugation & Probe Development: Utilized in the creation of labeled probes and bioconjugates for biochemical research and diagnostic applications, leveraging its aminoethyl functional group.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new small-molecule drugs targeting enzymes like thymidylate synthase.
• Chemical Biology Tool: Employed in the development of enzyme inhibitors and activity-based probes to study cellular processes involving pyrimidine metabolism.
• Custom Synthesis Building Block: Used by fine chemical suppliers for the contract manufacturing of complex, customer-specific molecules for clinical trials.

Basic Information

Product Name	n-(2-Aminoethyl)-2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetamide
CAS No.	546145-03-3
Molecular Formula	C9H14N4O3
Molecular Weight	226.23 g/mol
Synonyms	1-(2-Aminoethylcarbamoylmethyl)-5-methylpyrimidine-2,4-dione; 2-[(2-Aminoethyl)amino]-2-oxoethyl 5-methyl-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carboxylate; 5-Methyl-1-[2-oxo-2-[(2-aminoethyl)amino]ethyl]pyrimidine-2,4(1H,3H)-dione; N1-(2-Aminoethyl)-N2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)glycinamide; Thymine-1-acetic acid (2-aminoethyl)amide
EINECS	Contact for details

Quality Control

Our n-(2-Aminoethyl)-2-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Acetamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.