Description

2-Propynal, 3-(5-Fluoro-2-Pyrimidinyl)- (9Ci) is a specialized fluorinated pyrimidine derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular architecture, which incorporates both a reactive propynal group and a fluorinated heterocyclic system, enabling precise modifications in complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and antiviral research, where the fluoropyrimidine moiety is a privileged scaffold.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators that require fluorinated active ingredients.
• Material Science Research: Serves as a precursor for creating specialized monomers or ligands used in advanced polymers, coatings, or metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes and tags for studying biological mechanisms and target engagement.
• Academic & Contract Research: A critical reagent for universities and CROs (Contract Research Organizations) engaged in methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	2-Propynal, 3-(5-Fluoro-2-Pyrimidinyl)- (9Ci)
CAS No.	545425-80-7
Molecular Formula	C7H3FN2O
Molecular Weight	150.11 g/mol
Synonyms	3-(5-Fluoropyrimidin-2-yl)prop-2-ynal; 5-Fluoro-2-pyrimidinylpropynal; 3-(5-Fluoro-2-pyrimidinyl)-2-propynal; 2-Propyn-1-one, 3-(5-fluoro-2-pyrimidinyl)-; (5-Fluoro-2-pyrimidinyl)propiolaldehyde
EINECS	Contact for details

Quality Control

We supply 2-Propynal, 3-(5-Fluoro-2-Pyrimidinyl)- (9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For custom synthesis or specific pharmacopeial grade requirements (e.g., GMP standards), please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store the material at 2-8°C under an inert atmosphere. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.