Description

2-Propyn-1-Ol,3-(5-Fluoro-2-Pyrimidinyl)-(9Ci) is a specialized fluorinated pyrimidine derivative bearing a propargyl alcohol functional group. This unique molecular architecture makes it a high-value intermediate for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on creating new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the fluoropyrimidine moiety is critical for bioactivity.
• Chemical Biology Probe Synthesis: The alkyne group enables click chemistry applications for labeling and studying biological systems.
• Material Science Research: Serves as a monomer or precursor for creating specialized polymers with tailored electronic or optical properties.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for method development and novel compound library synthesis.

Basic Information

Product Name	2-Propyn-1-Ol,3-(5-Fluoro-2-Pyrimidinyl)-(9Ci)
CAS No.	545421-84-9
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	3-(5-Fluoropyrimidin-2-yl)prop-2-yn-1-ol; 5-Fluoro-2-(3-hydroxy-1-propynyl)pyrimidine; 2-Propyn-1-ol, 3-(5-fluoro-2-pyrimidinyl)-; (5-Fluoro-2-pyrimidinyl)propargyl alcohol; Propargyl alcohol, 3-(5-fluoro-2-pyrimidinyl)-; 545421-84-9; 3-(5-Fluoro-pyrimidin-2-yl)-prop-2-yn-1-ol
EINECS	Contact for details

Quality Control

Our production of 2-Propyn-1-Ol,3-(5-Fluoro-2-Pyrimidinyl)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.