Description

(As)-α-Amino-3-[(4-Carboxyphenyl)Methyl]-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid is a high-purity, non-natural amino acid derivative featuring a complex pyrimidinedione and phenylpropanoic acid structure. This compound is of significant interest for advanced research and development, particularly in the synthesis of novel pharmaceutical intermediates and bioactive molecules. It serves as a critical building block for medicinal chemists and R&D teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking to explore new therapeutic modalities.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Bioconjugation & Probe Development: The carboxylic acid and amino functionalities enable its use in creating labeled probes, linkers, and bioconjugates for diagnostic applications.
• Peptidomimetic Synthesis: Incorporated into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Chemical Biology Tool: Employed in studying enzyme mechanisms or as a component in the design of enzyme inhibitors.
• Fine Chemical Synthesis: Serves as a specialized starting material for the production of complex, high-value organic compounds.

Basic Information

Product Name	(As)-α-Amino-3-[(4-Carboxyphenyl)Methyl]-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid
CAS No.	544697-47-4
Molecular Formula	C15H15N3O6
Molecular Weight	333.30 g/mol
Synonyms	2-Amino-3-[4-(carboxymethyl)phenyl]propanoic acid derivative; 3-[(4-Carboxyphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-propanoic acid; (αS)-α-Amino-1,2,3,4-tetrahydro-3-[(4-carboxyphenyl)methyl]-2,4-dioxo-5-pyrimidinepropanoic acid; 5-Pyrimidinepropanoic acid derivative; CAS 544697-47-4; Amino-dioxo-pyrimidinepropanoic acid; AADPP
EINECS	Contact for details

Quality Control

Every batch of (As)-α-Amino-3-[(4-Carboxyphenyl)Methyl]-3,4-Dihydro-2,4-Dioxo-1(2H)-Pyrimidinepropanoic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment ensures material suitability for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.