Description

Pyrimidine, 4-Ethynyl-2-(Methylthio)- (9Ci) is a specialized heterocyclic building block featuring both an ethynyl and a methylthio functional group on its pyrimidine core. This unique structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced active ingredients for crop protection products.
• Material Science: Acts as a precursor for functionalized polymers or ligands in catalytic systems.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry due to its reactive ethynyl group.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic chemistry.

Basic Information

Product Name	Pyrimidine, 4-Ethynyl-2-(Methylthio)- (9Ci)
CAS No.	544675-64-1
Molecular Formula	C7H6N2S
Molecular Weight	150.20 g/mol
Synonyms	4-Ethynyl-2-(methylthio)pyrimidine; 2-(Methylthio)-4-ethynylpyrimidine; 4-Ethynyl-2-methylsulfanylpyrimidine; 4-Ethynyl-2-methylmercaptopyrimidine; 544675-64-1; 4-Ethynyl-2-(methylsulfanyl)pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Ethynyl-2-(Methylthio)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.