Description

3-(2-Chloro-5-(Trifluoromethyl)Phenyl)Benzaldehyde is a high-purity aromatic aldehyde building block featuring a chlorinated and trifluoromethylated biphenyl core. This compound is valued for its unique molecular architecture, which combines halogen and fluorine substituents to impart specific electronic and steric properties critical for advanced synthesis. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its rigid, substituted biphenyl structure.
• Cross-Coupling Reactions: The aldehyde functionality and aryl chloride moiety make it a versatile substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for custom synthesis projects requiring high-purity, complex aromatic aldehydes.

Basic Information

Product Name	3-(2-Chloro-5-(Trifluoromethyl)Phenyl)Benzaldehyde
CAS No.	544474-55-7
Molecular Formula	C14H8ClF3O
Molecular Weight	284.66 g/mol
Synonyms	[2-Chloro-5-(trifluoromethyl)phenyl](3-formylphenyl)methanone (tautomer); 3-[2-Chloro-5-(trifluoromethyl)phenyl]benzaldehyde; 2'-Chloro-α,α,α-trifluoro-5'-formyl-1,1'-biphenyl-3-carboxaldehyde; Benzaldehyde, 3-[2-chloro-5-(trifluoromethyl)phenyl]-; 544474-55-7; 3-(2-Chloro-5-trifluoromethylphenyl)benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chloro-5-(Trifluoromethyl)Phenyl)Benzaldehyde is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.