Description

1-(3-(Dimethylamino)Propyl)-2-(4-Nitrophenyl)-5,6,7,8-Tetrahydroquinazoline-4(1H)-Thione is a specialized heterocyclic organic compound featuring a tetrahydroquinazoline core. This molecule is of significant interest in advanced chemical synthesis due to its unique structural framework, which combines a thione group with a dimethylaminopropyl side chain and a nitrophenyl substituent. It serves as a critical pharmaceutical intermediate and a versatile building block for researchers and manufacturers in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds for agrochemical and material science applications.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in R&D laboratories.
• Biochemical Probe Development: Utilized in the design and synthesis of probes for studying biological processes and target identification.

Basic Information

Product Name	1-(3-(Dimethylamino)Propyl)-2-(4-Nitrophenyl)-5,6,7,8-Tetrahydroquinazoline-4(1H)-Thione
CAS No.	537680-84-5
Molecular Formula	C19H24N4O2S
Molecular Weight	372.48 g/mol
Synonyms	4(1H)-Thione, 1-[3-(Dimethylamino)propyl]-2-(4-nitrophenyl)-5,6,7,8-tetrahydroquinazoline; 1-(3-Dimethylaminopropyl)-2-(4-nitrophenyl)-5,6,7,8-tetrahydro-4(1H)-quinazolinethione; 2-(4-Nitrophenyl)-1-[3-(dimethylamino)propyl]-5,6,7,8-tetrahydro-4(1H)-quinazolinethione; 537680-84-5; Tetrahydroquinazolinethione derivative
EINECS	Contact for details

Quality Control

Our 1-(3-(Dimethylamino)Propyl)-2-(4-Nitrophenyl)-5,6,7,8-Tetrahydroquinazoline-4(1H)-Thione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to cGMP principles ensures reliable material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.