Description

6-(4-(4-Fluorophenyl)Piperazin-1-Yl)-9H-Purine is a high-purity, heterocyclic organic compound featuring a purine core linked to a fluorophenylpiperazine moiety, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. Pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers need this precise building block to synthesize and screen new drug candidates targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and receptor modulators.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and high-throughput screening (HTS) campaigns to study purinergic signaling pathways.
• Oncology Drug Discovery: Employed in the synthesis of potential anti-cancer agents targeting specific protein kinases involved in cell proliferation and survival.
• CNS Drug Development: Utilized as a building block for creating compounds intended to interact with neurological receptors for potential treatments of psychiatric and neurodegenerative conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up processes under cGMP guidelines for clinical trial material production.
• Academic Research: Serves as a specialized chemical for universities and research institutes conducting medicinal chemistry and pharmacology studies.

Basic Information

Product Name	6-(4-(4-Fluorophenyl)Piperazin-1-Yl)-9H-Purine
CAS No.	537667-18-8
Molecular Formula	C15H15FN6
Molecular Weight	298.32 g/mol
Synonyms	6-[4-(4-Fluorophenyl)piperazin-1-yl]-9H-purine; 6-(4-(4-Fluorophenyl)-1-piperazinyl)-9H-purine; 9H-Purine, 6-[4-(4-fluorophenyl)-1-piperazinyl]-; 537667-18-8; 6-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-purine; 6-(4-(4-Fluorophenyl)piperazin-1-yl)purine
EINECS	Contact for details

Quality Control

Our 6-(4-(4-Fluorophenyl)Piperazin-1-Yl)-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.