Description

1-(9H-Purin-6-Yl)Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a purine-piperidine hybrid structure. This compound is valued for its role as a critical building block in the synthesis of targeted small molecule therapeutics, particularly in oncology and antiviral research. It is essential for medicinal chemistry R&D and process development teams in the pharmaceutical and biotechnology industries seeking to develop novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of purine-based kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Oncology Drug Development: Serves as a core scaffold for compounds targeting specific cancer pathways.
• Antiviral Agent Synthesis: Employed in the research and development of nucleotide analog-based antiviral medications.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study purinergic signaling and related biological mechanisms.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and the production of clinical trial materials (CTM).

Basic Information

Product Name	1-(9H-Purin-6-Yl)Piperidine-4-Carboxamide
CAS No.	537667-04-2
Molecular Formula	C11H14N6O
Molecular Weight	246.27 g/mol
Synonyms	1-(9H-Purin-6-yl)piperidine-4-carboxamide; 1-(1H-Purin-6-yl)piperidine-4-carboxamide; 4-Carbamoyl-1-(9H-purin-6-yl)piperidine; 6-(4-Carbamoylpiperidin-1-yl)-9H-purine; Piperidine-4-carboxamide, 1-(9H-purin-6-yl)-; 1-(9H-Purin-6-yl)-4-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-(9H-Purin-6-Yl)Piperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the rigorous standards required for pharmaceutical R&D and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.