Description

4-Chloro-2,3,6-Trifluorobenzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by its unique substitution pattern. This compound is critical for the synthesis of complex molecules where the introduction of specific halogen and fluorine atoms is required for modulating electronic properties and biological activity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a valuable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Organic Synthesis & Research: A versatile building block in academic and industrial R&D for constructing complex heterocycles and fluorinated aromatic systems.

Basic Information

Item	Detail
Product Name	4-Chloro-2,3,6-Trifluorobenzaldehyde
CAS No.	537033-61-7
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,3,6-Trifluoro-4-chlorobenzaldehyde; 4-Chloro-2,3,6-trifluorobenzenecarboxaldehyde; Benzaldehyde, 4-chloro-2,3,6-trifluoro-; 4-Chloro-2,3,6-trifluoro benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2,3,6-Trifluorobenzaldehyde is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening sealed containers to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.