Description

7-(4-Chlorobenzyl)-1,3-Dimethyl-8-((2-(Piperidin-1-Yl)Ethyl)Thio)-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, synthetically derived xanthine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate for the synthesis of novel therapeutic agents, offering a structurally complex scaffold for medicinal chemistry exploration. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel adenosine receptor antagonists and other purine-based therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Tool Compound: Employed in in vitro assays to study purinergic signaling pathways and receptor interactions.
• Preclinical Development: Serves as an advanced intermediate for producing compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in neuropharmacology and cardiovascular diseases.

Basic Information

Product Name	7-(4-Chlorobenzyl)-1,3-Dimethyl-8-((2-(Piperidin-1-Yl)Ethyl)Thio)-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	536719-40-1
Molecular Formula	C21H26ClN5O2S
Molecular Weight	447.98 g/mol
Synonyms	8-[(2-Piperidin-1-ylethyl)sulfanyl]-7-[(4-chlorophenyl)methyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1H-Purine-2,6-dione, 3,7-dihydro-7-[(4-chlorophenyl)methyl]-1,3-dimethyl-8-[[2-(1-piperidinyl)ethyl]thio]-; 7-(4-Chlorobenzyl)-1,3-dimethyl-8-((2-(piperidin-1-yl)ethyl)thio)-3,7-dihydro-1H-purine-2,6-dione; Xanthine derivative, 8-thioether substituted; Purine-2,6-dione derivative
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development under GMP-like conditions for research use and can scale processes according to cGMP guidelines for later-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.