Description

Benzenemethanamine, α-Cyclopropyl-4-Ethoxy-3-Fluoro- (9Ci) is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a cyclopropyl-substituted benzenemethanamine core with ethoxy and fluorine substituents, enabling precise modulation of electronic and steric properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where the introduction of fluorine is critical for enhancing metabolic stability, bioavailability, or binding affinity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorinated aromatic moiety imparts desired biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and functional organic materials with tailored electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-functional aromatic amines.

Basic Information

Product Name	Benzenemethanamine, α-Cyclopropyl-4-Ethoxy-3-Fluoro- (9Ci)
CAS No.	535926-53-5
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	α-Cyclopropyl-4-ethoxy-3-fluorobenzylamine; 1-(Cyclopropyl)-1-(4-ethoxy-3-fluorophenyl)methanamine; 4-Ethoxy-3-fluoro-α-cyclopropylbenzenemethanamine; (4-Ethoxy-3-fluorophenyl)(cyclopropyl)methanamine; 535926-53-5; Benzenemethanamine, α-cyclopropyl-4-ethoxy-3-fluoro-
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, α-Cyclopropyl-4-Ethoxy-3-Fluoro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.