Description

Benzenemethanamine, α-Cyclopropyl-2-Ethoxy-5-Fluoro- (9Ci) is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique cyclopropyl and ethoxy-fluoro substituted benzylamine structure enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorinated aromatic moiety for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or functionalization agent for creating specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function or cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Benzenemethanamine, α-Cyclopropyl-2-Ethoxy-5-Fluoro- (9Ci)
CAS No.	535926-52-4
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	α-Cyclopropyl-2-ethoxy-5-fluorobenzylamine; 1-(2-Ethoxy-5-fluorophenyl)-1-cyclopropylmethanamine; 2-Ethoxy-5-fluoro-α-(cyclopropyl)benzenemethanamine; (2-Ethoxy-5-fluorophenyl)(cyclopropyl)methanamine; Benzylamine, α-cyclopropyl-2-ethoxy-5-fluoro-; 535926-52-4; (Cyclopropyl)(2-ethoxy-5-fluorophenyl)methanamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and development, with typical purity levels exceeding 95% (by HPLC). Each batch is accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.