Description

Carbamic Acid, (3-Amino-2,6-Difluorophenyl)-, 1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector where precise chemical architecture is paramount. It is essential for research chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials that require a difluorinated aniline scaffold.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging the stability and bioactivity of the difluorophenyl group.
• Peptide Mimetics & PROTACs: Serves as a protected amino acid component in the construction of peptide-like molecules and proteolysis-targeting chimeras (PROTACs).
• Material Science: Employed in the synthesis of specialty polymers and advanced organic materials that incorporate fluorinated aromatic units for enhanced properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags and molecular probes for biological imaging and diagnostic applications.
• Scale-Up Process Chemistry: Provides a reliable and well-defined starting material for process optimization and kilogram-scale production in fine chemical manufacturing.

Basic Information

Product Name	Carbamic Acid, (3-Amino-2,6-Difluorophenyl)-, 1,1-Dimethylethyl Ester
CAS No.	535170-20-8
Molecular Formula	C11H14F2N2O2
Molecular Weight	244.24 g/mol
Synonyms	tert-Butyl (3-amino-2,6-difluorophenyl)carbamate; N-Boc-3-amino-2,6-difluoroaniline; 1,1-Dimethylethyl N-(3-amino-2,6-difluorophenyl)carbamate; 3-Amino-2,6-difluorophenylcarbamic acid tert-butyl ester; Boc-3-A-2,6-DFA; (3-Amino-2,6-difluorophenyl)carbamic Acid tert-Butyl Ester; tert-Butyl N-(3-amino-2,6-difluorophenyl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Amino-2,6-Difluorophenyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.