Description

2,6-Difluoro-4-Hydroxybenzaldehyde is a fluorinated aromatic aldehyde derivative that serves as a versatile and high-value synthetic intermediate. Its unique structure, featuring both aldehyde and phenolic hydroxyl groups flanked by fluorine atoms, makes it a critical building block for the development of advanced materials and active pharmaceutical ingredients. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides where the difluoro-hydroxybenzaldehyde scaffold contributes to bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated core structures for high-performance liquid crystal displays (LCDs) and organic light-emitting diode (OLED) materials, enhancing electronic properties and thermal stability.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, epoxy resins, and coatings to impart specific chemical resistance and physical properties.
• Complex Ligand & Catalyst Preparation: Utilized in organometallic chemistry to create sophisticated chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: Acts as a starting material for synthesizing fluorophores and molecular sensors used in bio-imaging and diagnostic applications.

Basic Information

Product Name	2,6-Difluoro-4-Hydroxybenzaldehyde
CAS No.	532967-21-8
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	4-Hydroxy-2,6-difluorobenzaldehyde; 2,6-Difluoro-4-hydroxybenzaldehyde; 2,6-Difluoro-4-formylphenol; 4-Formyl-3,5-difluorophenol; Benzaldehyde, 2,6-difluoro-4-hydroxy-; 3,5-Difluoro-4-hydroxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Hydroxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for prolonged storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.