Description

2-[(6-Amino-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Thio]Propanoic Acid is a high-purity, sulfur-containing heterocyclic carboxylic acid derivative. This compound is a critical building block in pharmaceutical research and development, valued for its unique molecular scaffold that combines pyrimidine and thioether functionalities. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the pyrimidine-thioether motif is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage its heterocyclic structure.
• Bioconjugation & Probe Synthesis: The carboxylic acid group enables coupling reactions for creating biochemical probes, diagnostic agents, or targeted drug conjugates.
• Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced polymers or metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical entities.

Basic Information

Product Name	2-[(6-Amino-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Thio]Propanoic Acid
CAS No.	532954-30-6
Molecular Formula	C7H9N3O3S
Molecular Weight	215.23 g/mol
Synonyms	2-[(6-Amino-4-oxo-1,4-dihydro-2-pyrimidinyl)thio]propanoic acid; 2-(6-Amino-4-oxo-1,4-dihydropyrimidin-2-ylthio)propionic acid; 2-[(6-Amino-4-oxo-1H-pyrimidin-2-yl)thio]propanoic acid; 2-Mercaptopropionic acid pyrimidine derivative; 6-Amino-2-mercaptopyrimidin-4-ol propanoic acid derivative; 2-Thiopropanoic acid, (6-amino-4-oxo-1,4-dihydro-2-pyrimidinyl)-; (6-Amino-4-oxo-1,4-dihydropyrimidin-2-ylthio)propanoic acid
EINECS	Contact for details

Quality Control

Our 2-[(6-Amino-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Thio]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.