Description

5-Bromo-2-Fluoro-4-Iodophenol is a highly functionalized halogenated phenol derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique combination of bromo, fluoro, and iodo substituents on a phenolic scaffold makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its phenolic and halogen functionalities.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Iodophenol
CAS No.	530141-46-9
Molecular Formula	C6H3BrFIO
Molecular Weight	316.89 g/mol
Synonyms	4-Iodo-5-bromo-2-fluorophenol; 2-Fluoro-4-iodo-5-bromophenol; Phenol, 5-bromo-2-fluoro-4-iodo-; 5-Bromo-2-fluoro-4-iodo-1-hydroxybenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Iodophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical data. Our quality commitment supports applications in GMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.