Description

H-Glu-Leu-Asp-[(2R,4S,5S)-5-Amino-4-Hydroxy-2,7-Dimethyl-Octanoyl]-Val-Glu-Phe-Gly-Gly-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Oh is a complex, custom-designed peptide sequence featuring a unique, branched-chain fatty acyl modification. This compound is engineered for high-affinity binding and targeted biological activity, making it a critical intermediate in advanced therapeutic research. It is primarily utilized by pharmaceutical R&D and biotechnology organizations focused on developing novel peptide-based drugs and diagnostic agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel peptide therapeutics.
• Cell Penetrating Peptide (CPP) Studies: The poly-D-arginine tail is designed for enhanced cellular uptake, making it valuable for drug delivery system research.
• Targeted Drug Conjugates: The specific sequence and modification allow for the creation of conjugates targeting specific receptors or pathways.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific protein-protein interactions, signal transduction, or enzyme inhibition.
• Preclinical Development: Supports efficacy and pharmacokinetic studies for new molecular entities in animal models.
• Diagnostic Agent Development: Potential use in developing targeted imaging probes due to its specific binding characteristics.

Basic Information

Item	Detail
Product Name	H-Glu-Leu-Asp-[(2R,4S,5S)-5-Amino-4-Hydroxy-2,7-Dimethyl-Octanoyl]-Val-Glu-Phe-Gly-Gly-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Oh
CAS No.	527674-72-2
Molecular Formula	C124H224N52O30
Molecular Weight	Contact for details
Synonyms	Custom Fatty Acylated Poly-D-Arginine Peptide; Glu-Leu-Asp-Ahdo-Val-Glu-Phe-Gly-Gly-D-Arg9-OH; (2R,4S,5S)-AHDO-modified CPP peptide; Poly-D-arginine nonapeptide conjugate; Research Peptide 527674-72-2; Cell-penetrating peptide intermediate; Branched-chain lipopeptide
EINECS	Contact for details

Quality Control

This high-purity peptide is manufactured under strict GMP-like conditions for research use. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, MS, and amino acid analysis. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.