Description

Phenol, 4-Amino-2-Chloro-5-Fluoro- is a halogenated and aminated phenol derivative, serving as a versatile and high-value synthetic intermediate. Its molecular structure makes it a critical building block for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, where the chloro-fluoro substitution pattern can enhance biological activity and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, dyes, and advanced organic electronic materials.
• Biochemical Tool Compound: Utilized in academic and industrial research as a probe or scaffold for studying enzyme inhibition and receptor binding, leveraging its phenolic and amino functionalities.

Basic Information

Product Name	Phenol, 4-Amino-2-Chloro-5-Fluoro-
CAS No.	524955-76-8
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	2-Chloro-5-fluoro-4-aminophenol; 4-Amino-2-chloro-5-fluorophenol; 5-Fluoro-2-chloro-4-aminophenol; 2-Chloro-5-fluoro-4-hydroxyaniline; 4-Amino-2-chloro-5-fluorohydroxybenzene; ACFP; 4-Amino-2-chloro-5-fluoro-1-hydroxybenzene
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows cGMP principles where applicable, and each batch is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.