Description

6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique halogenated and trifluoromethoxy-substituted structure, which is critical for modulating the physicochemical properties of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its role as a key intermediate enables the exploration of new chemical spaces in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde
CAS No.	524674-70-2
Molecular Formula	C8H3BrF4O2
Molecular Weight	287.01 g/mol
Synonyms	2-Fluoro-6-bromo-3-(trifluoromethoxy)benzaldehyde; 3-Bromo-6-fluoro-2-(trifluoromethoxy)benzaldehyde; 6-Bromo-2-fluoro-3-(trifluoromethoxy)benzaldehyde; Benzaldehyde, 6-bromo-2-fluoro-3-(trifluoromethoxy)-; 524674-70-2
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.