Description

(2E)-2-[(8-Ethoxy-4-Methylquinazolin-2-Yl)Imino]-1,2,5,6,7,8-Hexahydroquinazolin-4-Ol is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. Its complex molecular structure makes it a critical building block for the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. This compound is essential for pharmaceutical R&D teams and fine chemical manufacturers focused on creating new therapeutic agents targeting a range of diseases.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological pathways and enzyme functions in academic and industrial laboratories.
• Fine Chemical Synthesis: Acts as a specialized building block for the multi-step synthesis of complex organic molecules in contract research and manufacturing organizations (CROs/CMOs).
• Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2E)-2-[(8-Ethoxy-4-Methylquinazolin-2-Yl)Imino]-1,2,5,6,7,8-Hexahydroquinazolin-4-Ol
CAS No.	524055-95-6
Molecular Formula	C20H23N5O2
Molecular Weight	365.43 g/mol
Synonyms	4(3H)-Quinazolinone, 2-[(8-ethoxy-4-methyl-2-quinazolinyl)imino]-1,2,5,6,7,8-hexahydro-; (2E)-2-[(8-Ethoxy-4-methylquinazolin-2-yl)imino]-1,2,5,6,7,8-hexahydro-4-quinazolinol; 2-((8-Ethoxy-4-methylquinazolin-2-yl)imino)-1,2,5,6,7,8-hexahydroquinazolin-4-ol; CAS 524055-95-6
EINECS	Contact for details

Quality Control

Our production of (2E)-2-[(8-Ethoxy-4-Methylquinazolin-2-Yl)Imino]-1,2,5,6,7,8-Hexahydroquinazolin-4-Ol adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research-grade and pharmaceutical intermediate specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency for your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.