Description

2-Amino-7-(4-tert-Butyl-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex quinazolinone-based molecular frameworks.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Biochemical Reagent: May be utilized in biochemical assays and as a reference standard for analytical method development.
• Material Science Research: Investigated for potential applications in the development of organic electronic materials due to its conjugated structure.

Basic Information

Product Name	2-Amino-7-(4-tert-Butyl-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One
CAS No.	523990-62-7
Molecular Formula	C18H21N3O
Molecular Weight	295.38 g/mol
Synonyms	2-Amino-7-(4-tert-butylphenyl)-7,8-dihydro-6H-quinazolin-5-one; 7-(4-tert-Butylphenyl)-2-amino-7,8-dihydro-5(6H)-quinazolinone; 523990-62-7; 2-Amino-7-(p-tert-butylphenyl)-5,6,7,8-tetrahydroquinazolin-5-one; tert-Butylphenyl-dihydroquinazolinone amine; AQO intermediate; Quinazolinone derivative CAS 523990-62-7
EINECS	Contact for details

Quality Control

Our 2-Amino-7-(4-tert-Butyl-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.