Description

1-(4-Methoxyphenyl)-2-(4-Oxo-1,4,5,6,7,8-Hexahydroquinazolin-2-Yl)Guanidine is a high-purity, complex organic compound featuring a guanidine moiety linked to a methoxyphenyl and a partially saturated quinazolinone ring system. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting enzyme inhibition or receptor modulation.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Serves as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Potential use in biochemical assays as a probe to study specific biological pathways or protein interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce complex guanidine and heterocyclic functionalities.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	1-(4-Methoxyphenyl)-2-(4-Oxo-1,4,5,6,7,8-Hexahydroquinazolin-2-Yl)Guanidine
CAS No.	522660-57-7
Molecular Formula	C₁₆H₁₉N₅O₂
Molecular Weight	313.36 g/mol
Synonyms	2-[[Amino-[(4-methoxyphenyl)amino]methylidene]amino]-5,6,7,8-tetrahydro-4(1H)-quinazolinone; 1-(4-Methoxyphenyl)-2-(4-oxo-5,6,7,8-tetrahydro-1H-quinazolin-2-yl)guanidine; Guanidine, N-(4-methoxyphenyl)-N'-(4-oxo-5,6,7,8-tetrahydro-1H-quinazolin-2-yl)-; 522660-57-7; 4-Oxo-1,4,5,6,7,8-hexahydroquinazolin-2-ylguanidine derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)-2-(4-Oxo-1,4,5,6,7,8-Hexahydroquinazolin-2-Yl)Guanidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.