Description

Benzeneacetonitrile, 5-Amino-2-Fluoro- (9Ci) is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino and a fluorine substituent on the aromatic ring, makes it a valuable precursor for constructing complex heterocycles and active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and agrochemical development. Its precise synthesis and high purity are critical for ensuring the success of downstream applications and final product efficacy.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of fluorinated bioactive molecules.
• Agrochemical Research: Used in creating advanced pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for nitrogen-containing ligands used in coordination chemistry and catalytic processes.
• Material Science: Employed in the research and development of specialty polymers and advanced organic electronic materials.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Benzeneacetonitrile, 5-Amino-2-Fluoro- (9Ci)
CAS No.	519059-10-0
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	5-Amino-2-fluorobenzyl cyanide; 2-Fluoro-5-aminobenzyl cyanide; (5-Amino-2-fluorophenyl)acetonitrile; 2-Fluoro-5-aminophenylacetonitrile; 5-Amino-2-fluorobenzeneacetonitrile; 2-Fluoro-5-aminobenzeneacetonitrile; α-(5-Amino-2-fluorophenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 5-Amino-2-Fluoro- (9Ci) is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.