Description

4-(6-Methoxy-2-Naphthyl)-6-(Trifluoromethyl)Pyrimidin-2-Amine is a high-value, specialized heterocyclic compound featuring a naphthyl and a trifluoromethyl group on a pyrimidine core, making it a critical building block for advanced chemical synthesis. Its unique structure offers significant potential for modulating the biological activity and physicochemical properties of target molecules. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science Precursor: Acts as a starting material for the development of advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	4-(6-Methoxy-2-Naphthyl)-6-(Trifluoromethyl)Pyrimidin-2-Amine
CAS No.	519056-66-7
Molecular Formula	C₁₆H₁₂F₃N₃O
Molecular Weight	319.28 g/mol
Synonyms	6-(Trifluoromethyl)-4-(6-methoxy-2-naphthyl)-2-pyrimidinamine; 4-(6-Methoxy-2-naphthalenyl)-6-(trifluoromethyl)-2-pyrimidinamine; 2-Amino-4-(6-methoxy-2-naphthyl)-6-(trifluoromethyl)pyrimidine; 4-(6-Methoxy-2-naphthyl)-6-trifluoromethylpyrimidin-2-ylamine; 519056-66-7; 4-(6-Methoxynaphthalen-2-yl)-6-(trifluoromethyl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our production of 4-(6-Methoxy-2-Naphthyl)-6-(Trifluoromethyl)Pyrimidin-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and is supported by a detailed Certificate of Analysis (COA). We are committed to meeting the exacting standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.