Description

6-(tert-Butylsulfonyl)-2-Methylpyrazolo[1,5-A]Pyrimidin-7-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in early-stage R&D.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for new chemical entities (NCEs).
• Biochemical Research: May be utilized as a tool compound or a ligand in biochemical assays and proteomics studies.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents, given the bioactivity of similar heterocyclic structures.

Basic Information

Product Name	6-(tert-Butylsulfonyl)-2-Methylpyrazolo[1,5-A]Pyrimidin-7-Amine
CAS No.	519056-49-6
Molecular Formula	C11H16N4O2S
Molecular Weight	268.34 g/mol
Synonyms	2-Methyl-6-[(2-methylpropan-2-yl)sulfonyl]pyrazolo[1,5-a]pyrimidin-7-amine; 6-(tert-Butylsulfonyl)-2-methyl-7H-pyrazolo[1,5-a]pyrimidin-7-amine; 2-Methyl-6-(tert-butylsulfonyl)pyrazolo[1,5-a]pyrimidin-7-amine; 7-Amino-6-(tert-butylsulfonyl)-2-methylpyrazolo[1,5-a]pyrimidine; 6-(tert-Butylsulfonyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine; tert-Butylsulfonyl pyrazolopyrimidine amine; CAS 519056-49-6
EINECS	Contact for details

Quality Control

Our 6-(tert-Butylsulfonyl)-2-Methylpyrazolopyrimidin-7-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.