Description

3-Benzyl-1-Cyclopropyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its tetrahydropyrimidine-dione core structure. This compound is of significant commercial interest due to its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of proprietary drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Synthesis: Acts as a versatile building block for constructing more complex nitrogen-containing heterocycles in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and novel reaction pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	3-Benzyl-1-Cyclopropyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile
CAS No.	519056-48-5
Molecular Formula	C₁₅H₁₃N₃O₂
Molecular Weight	267.29 g/mol
Synonyms	3-Benzyl-1-cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; 1-Cyclopropyl-3-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; 5-Cyano-3-benzyl-1-cyclopropylpyrimidine-2,4(1H,3H)-dione; 3-Benzyl-1-cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; Tetrahydropyrimidine-5-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 3-Benzyl-1-Cyclopropyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures reliable supply for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.