Description

4-Bromo-2-Fluoro-6-Nitroaniline is a halogenated and nitrated aniline derivative, serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents on an aniline core, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments that require specific light-fastness and color properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling the construction of biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostic applications.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-Nitroaniline
CAS No.	517920-70-6
Molecular Formula	C6H4BrFN2O2
Molecular Weight	235.01 g/mol
Synonyms	2-Fluoro-4-bromo-6-nitroaniline; 6-Amino-3-bromo-1-fluoro-2-nitrobenzene; 1-Amino-3-bromo-5-fluoro-2-nitrobenzene; 4-Bromo-2-fluoro-6-nitrobenzenamine; Aniline, 4-bromo-2-fluoro-6-nitro-; Benzenamine, 4-bromo-2-fluoro-6-nitro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-6-Nitroaniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.