Description

Fmoc-(R)-3-Amino-3-(2-Bromo-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This chiral building block is critical for introducing specific structural motifs and bromine-functionalized aromatic side chains into complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery and the development of novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of peptides containing brominated phenylalanine analogs.
• Medicinal Chemistry & Drug Discovery: A versatile intermediate for constructing peptide-based drug candidates, PROTACs, and molecular probes targeting various disease pathways.
• Chemical Biology Research: Used to incorporate a stable bromine handle into peptides and proteins for site-specific bioconjugation, labeling, or cross-linking studies via click chemistry (e.g., Suzuki coupling).
• Agrochemical Development: Serves as a chiral synthon in the research and synthesis of novel, biologically active compounds for crop protection.
• Material Science: A precursor for designing functionalized polymers and advanced materials with specific chiral and aromatic properties.

Basic Information

Product Name	Fmoc-(R)-3-Amino-3-(2-Bromo-Phenyl)-Propionic Acid
CAS No.	517905-84-9
Molecular Formula	C24H20BrNO4
Molecular Weight	466.33 g/mol
Synonyms	Fmoc-(R)-3-Amino-3-(2-bromophenyl)propanoic Acid; (R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-bromophenyl)propanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-bromophenyl)-D-β-homoalanine; Fmoc-D-2-BrPhe(3)-OH; Fmoc-3-amino-3-(2-bromophenyl)propionic acid; N-α-Fmoc-3-amino-3-(2-bromophenyl)propionic acid
EINECS	Contact for details

Quality Control

Our Fmoc-(R)-3-Amino-3-(2-Bromo-Phenyl)-Propionic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to high-purity standards suitable for pharmaceutical R&D, and custom purity grades or analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.