Description

2-Chloro-n-Methyl-5-(Trifluoromethyl)Pyrimidin-4-Amine is a high-value pyrimidine derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique trifluoromethyl and chloro-substituted pyrimidine core enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functionality into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require a pyrimidine backbone.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in advanced materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	2-Chloro-n-Methyl-5-(Trifluoromethyl)Pyrimidin-4-Amine
CAS No.	515824-43-8
Molecular Formula	C6H4ClF3N3
Molecular Weight	210.56 g/mol
Synonyms	2-Chloro-N-methyl-5-(trifluoromethyl)pyrimidin-4-amine; 4-Amino-2-chloro-N-methyl-5-(trifluoromethyl)pyrimidine; 2-Chloro-4-(methylamino)-5-(trifluoromethyl)pyrimidine; 515824-43-8; 2-Chloro-N-methyl-5-trifluoromethylpyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Methyl-5-(Trifluoromethyl)Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.