Description

4-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Butanoic Acid is a high-value, sulfur-containing pyrimidine derivative characterized by a phenyl ring and a trifluoromethyl group. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine-thioether scaffold.
• Chemical Synthesis Building Block: Employed in organic chemistry for constructing complex molecules via its reactive carboxylic acid and thioether functional groups.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique properties.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling and modifying biomolecules.

Basic Information

Item	Details
Product Name	4-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Butanoic Acid
CAS No.	514180-40-6
Molecular Formula	C15H13F3N2O2S
Molecular Weight	342.34 g/mol
Synonyms	4-[(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio]butanoic acid; 4-((4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)butyric acid; 2-[(4-Carboxybutyl)thio]-4-phenyl-6-(trifluoromethyl)pyrimidine; 4-Phenyl-6-(trifluoromethyl)-2-[(4-carboxybutyl)thio]pyrimidine; 514180-40-6; Butanoic acid, 4-[[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]thio]-
EINECS	Contact for details

Quality Control

Our 4-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Butanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.