Description

2-{[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid is a high-value, fluorinated pyrimidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both fluorine and trifluoromethyl substituents, is engineered to impart unique electronic and steric properties to target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, particularly in areas targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential intermediate in the synthesis of specialty chemicals and functional materials requiring fluorinated aromatic systems.

Basic Information

Product Name	2-{[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid
CAS No.	514180-15-5
Molecular Formula	C14H10F4N2O2S
Molecular Weight	346.30 g/mol
Synonyms	2-{[4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}propanoic acid; 2-({4-(4-Fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl}thio)propanoic Acid; 2-[(4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl)thio]propanoic acid; Propanoic acid, 2-[[4-(4-fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-; CAS 514180-15-5
EINECS	Contact for details

Quality Control

Our production of 2-{[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.