Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(3-Pyridinyl)-,2-Propenylester(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, especially those targeting the central nervous system or as kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis: Acts as a versatile precursor for constructing fused pyrimidine-pyridine ring systems in academic and industrial R&D laboratories.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Bioconjugation & Probe Development: The propenyl ester moiety can be utilized for further chemical modifications in creating biochemical probes or targeted drug conjugates.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-4-(3-Pyridinyl)-,2-Propenylester(9Ci)
CAS No.	512840-53-8
Molecular Formula	C15H15N3O3
Molecular Weight	285.30 g/mol
Synonyms	4-(3-Pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid 2-propenyl ester; Allyl 4-(pyridin-3-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 1,2,3,4-Tetrahydro-6-methyl-2-oxo-4-(3-pyridinyl)-5-pyrimidinecarboxylic acid 2-propenyl ester; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(3-pyridinyl)-, 2-propenyl ester; CAS 512840-53-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.