Description

3-Hydroxy-2-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-2,3-Dihydroquinazolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles due to its reactive functional groups.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Biochemical Tool Compound: Utilized in life sciences research as a probe or inhibitor to study specific enzymatic pathways or biological mechanisms.

Basic Information

Product Name	3-Hydroxy-2-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-2,3-Dihydroquinazolin-4(1H)-One
CAS No.	512809-24-4
Molecular Formula	C₁₅H₁₆N₄O₂
Molecular Weight	284.31 g/mol
Synonyms	3-Hydroxy-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinazolin-4-one; 2,3-Dihydro-3-hydroxy-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 2,3-dihydro-3-hydroxy-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)-; 512809-24-4; Quinazolinone derivative with trimethylpyrazole
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-2-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-2,3-Dihydroquinazolin-4(1H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.