Description

1H-Pyrazolo[3,4-D]Pyrimidine, 3-Bromo-1-Methyl-6-(Methylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant commercial importance. This compound is valued for its role as a key synthetic precursor in the development of targeted kinase inhibitors and other bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Development: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and inhibition mechanisms.
• Organic Synthesis: A versatile heterocyclic scaffold for constructing complex molecular architectures in academic and industrial research.

Basic Information

Product Name	1H-Pyrazolo[3,4-D]Pyrimidine, 3-Bromo-1-Methyl-6-(Methylsulfonyl)-
CAS No.	508220-98-2
Molecular Formula	C7H7BrN4O2S
Molecular Weight	291.13 g/mol
Synonyms	3-Bromo-1-methyl-6-(methylsulfonyl)-1H-pyrazolo[3,4-d]pyrimidine; 3-Bromo-1-methyl-6-methylsulfonyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 3-bromo-1-methyl-6-(methylsulfonyl)-; 508220-98-2; 3-Bromo-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl methyl sulfone; 3-Bromo-1-methyl-1H-pyrazolo[3,4-d]pyrimidine-6-sulfonic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-D]Pyrimidine, 3-Bromo-1-Methyl-6-(Methylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.