Description

Fmoc-(S)-3-Amino-3-(2-Trifluoromethyl-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis and pharmaceutical research. This compound is a critical building block for constructing complex peptide chains with enhanced stability and specific biological activity. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical discovery, and advanced material science who require precise, high-quality chiral intermediates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, enabling the controlled assembly of novel peptides.
• Pharmaceutical Intermediates: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetic Drug Design: Used to incorporate a trifluoromethylphenyl side chain into peptide backbones, enhancing metabolic stability, lipophilicity, and receptor binding affinity.
• Agrochemical Research: Employed in the development of novel peptide-based pesticides and herbicides with improved efficacy.
• Bioconjugation and Probe Development: Useful for creating labeled peptides or affinity probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable tool for studying protein-protein interactions and developing new therapeutic modalities in both academic and commercial research laboratories.

Basic Information

Product Name	Fmoc-(S)-3-Amino-3-(2-Trifluoromethyl-Phenyl)-Propionic Acid
CAS No.	507472-19-7
Molecular Formula	C25H20F3NO4
Molecular Weight	455.43 g/mol
Synonyms	Fmoc-3-Amino-3-(2-trifluoromethylphenyl)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-3-[2-(trifluoromethyl)phenyl]propanoic acid; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-3-(2-(trifluoromethyl)phenyl)propanoic acid; Fmoc-Atfmp-OH; Fmoc-β3-homoTfmPhe-OH; Fmoc-(S)-3-Amino-3-(2-TFM-Phenyl)-Propionic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-3-(2-Trifluoromethyl-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.