Description

Ethyl 3-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoate is a high-value, sulfur-containing pyrimidine derivative, recognized for its role as a key synthetic intermediate in advanced organic chemistry. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active ingredients. Pharmaceutical, agrochemical, and material science researchers need this intermediate for its trifluoromethyl and phenyl-substituted pyrimidine core, which is instrumental in creating compounds with enhanced biological activity and specific physical properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethylpyrimidine moiety can contribute to improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring this specific molecular architecture.

Basic Information

Product Name	Ethyl 3-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoate
CAS No.	505064-91-5
Molecular Formula	C₁₆H₁₅F₃N₂O₂S
Molecular Weight	356.36 g/mol
Synonyms	Ethyl 3-((4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanoate; 2-(((4-Phenyl-6-(trifluoromethyl)-2-pyrimidinyl)thio)ethyl propionate; Propanoic acid, 3-((4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl)thio)-, ethyl ester; Ethyl 3-[(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)sulfanyl]propanoate
EINECS	Contact for details

Quality Control

Our Ethyl 3-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.