Description

2-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted pyrimidine-thioether scaffold. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. Research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries need this precise building block to develop new drugs and crop protection agents with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel small-molecule drugs, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Chemical Biology Probe: Serves as a valuable scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of specialty polymers with specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid
CAS No.	505054-76-2
Molecular Formula	C14H11F3N2O2S
Molecular Weight	328.31 g/mol
Synonyms	2-[(4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio]propanoic acid; 2-({4-Phenyl-6-[(trifluoromethyl)pyrimidin-2-yl]thio})propionic acid; α-[(4-Phenyl-6-(trifluoromethyl)-2-pyrimidinyl)thio]propionic Acid; 2-((4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanoic acid; Propanoic acid, 2-[[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]thio]-; CAS 505054-76-2
EINECS	Contact for details

Quality Control

Every batch of 2-{[4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Propanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with exacting industry and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and supply chain reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.