Description

{[4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is a high-value, multifunctional heterocyclic building block and intermediate. Its core value proposition lies in its unique molecular architecture, combining a pyrimidine core with thiophene and trifluoromethyl groups, which is essential for imparting specific biological activity and physicochemical properties in advanced synthetic applications. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its CAS number is 505054-60-4.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the pyrimidine-thiophene scaffold is pharmacologically active.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyrimidine moiety.
• Material Science: Serves as a specialized monomer or additive in the creation of advanced polymers and organic electronic materials due to its conjugated system.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagging reagent to study protein-ligand interactions and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical building block for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	{[4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid
CAS No.	505054-60-4
Molecular Formula	C11H7F3N2O2S2
Molecular Weight	320.31 g/mol
Synonyms	2-({4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl}thio)acetic acid; [4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanylacetic acid; 2-[[4-(2-Thienyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]acetic acid; 505054-60-4; TTPA; Thienyl-trifluoromethyl-pyrimidine-thioacetic acid
EINECS	Contact for details

Quality Control

Our {[4-Thien-2-Yl-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.