Description

4-(1,3-Benzodioxol-5-Yl)-6-(Trifluoromethyl)Pyrimidine-2-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in therapeutic areas targeting the central nervous system.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic molecules due to its reactive thiol and pyrimidine groups.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring novel chemical reactions.

Basic Information

Product Name	4-(1,3-Benzodioxol-5-Yl)-6-(Trifluoromethyl)Pyrimidine-2-Thiol
CAS No.	505053-95-2
Molecular Formula	C12H7F3N2O2S
Molecular Weight	300.26 g/mol
Synonyms	4-(1,3-Benzodioxol-5-yl)-6-(trifluoromethyl)-2-pyrimidinethiol; 4-(Benzo[d][1,3]dioxol-5-yl)-6-(trifluoromethyl)pyrimidine-2-thiol; 2-Mercapto-4-(3,4-methylenedioxyphenyl)-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-(1,3-benzodioxol-5-yl)-2-pyrimidinethiol; 4-(3,4-Methylenedioxyphenyl)-6-(trifluoromethyl)-2-pyrimidinethiol; 4-(1,3-Benzodioxol-5-yl)-6-(trifluoromethyl)-2-mercaptopyrimidine
EINECS	Contact for details

Quality Control

Our 4-(1,3-Benzodioxol-5-Yl)-6-(Trifluoromethyl)Pyrimidine-2-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.