Description

{[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-thioacetic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated pyrimidine core.
• Chemical Research & Development: Serves as a versatile synthon in organic chemistry for constructing complex heterocyclic systems in academic and industrial R&D labs.
• Material Science Precursor: Potential application in the synthesis of specialty polymers and ligands for catalytic systems.

Basic Information

Product Name	{[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid
CAS No.	505049-36-5
Molecular Formula	C₁₃H₈F₄N₂O₂S
Molecular Weight	332.27 g/mol
Synonyms	2-({[4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl})acetic acid; [4-(4-Fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]thioacetic Acid; 2-[[4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl]thio]acetic acid; (4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetic acid; CAS 505049-36-5
EINECS	Contact for details

Quality Control

Our {[4-(4-Fluorophenyl)-6-(Trifluoromethyl)Pyrimidin-2-Yl]Thio}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.