Description

Apixaban CAS NO 503612-47-3 is a highly potent, selective, and orally active direct Factor Xa inhibitor. This compound is a critical active pharmaceutical ingredient (API) used in the manufacture of anticoagulant medications. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of therapies to prevent and treat thromboembolic disorders, such as stroke and deep vein thrombosis.

Application

• Primary use as the Active Pharmaceutical Ingredient (API) in the commercial production of oral anticoagulant tablets.
• Research and development of novel antithrombotic and anticoagulant drug formulations.
• Manufacturing of generic pharmaceutical products following patent expiry.
• Use in clinical trial materials for studying new indications or dosage forms.
• Reference standard in analytical and quality control laboratories for method development and validation.
• Biochemical research targeting the coagulation cascade and Factor Xa enzyme activity.

Basic Information

Product Name	Apixaban
CAS No.	503612-47-3
Molecular Formula	C25H25N5O4
Molecular Weight	459.50 g/mol
Synonyms	BMS-562247; BMS-562247-01; Eliquis (Trade Name); 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; UNII-3Z9Y7UWC1J
EINECS	Contact for details

Quality Control

Our Apixaban is manufactured under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. We provide material that complies with relevant pharmacopeial monographs (e.g., USP, EP) for use as an API. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring full traceability and regulatory support for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.