Description

1-(3-(Trifluoromethyl)Phenyl)Cyclopropanamine is a high-value, fluorinated aromatic amine building block featuring a cyclopropane ring. This compound matters for its unique structural motif, which combines the metabolic stability and lipophilicity imparted by the trifluoromethyl group with the conformational constraint of the cyclopropane ring. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients and functional molecules, particularly in lead optimization and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in CNS and oncology therapeutic areas.
• Agrochemical Synthesis: Used as a building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atom's properties.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis.
• Material Science Research: Incorporated into monomers or additives to create specialty polymers with tailored properties.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme mechanisms or protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for bespoke chemical synthesis services at milligram to kilogram scale.

Basic Information

Product Name	1-(3-(Trifluoromethyl)Phenyl)Cyclopropanamine
CAS No.	503417-34-3
Molecular Formula	C10H10F3N
Molecular Weight	201.19 g/mol
Synonyms	[1-(3-Trifluoromethylphenyl)cyclopropyl]amine; 1-[3-(Trifluoromethyl)phenyl]cyclopropanamine; 1-(3-(Trifluoromethyl)phenyl)cyclopropan-1-amine; α-(Trifluoromethyl)cyclopropylamine; 3-(Trifluoromethyl)benzenecyclopropanamine; 1-(m-Trifluoromethylphenyl)cyclopropylamine; 3-(Aminocyclopropyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 1-(3-(Trifluoromethyl)Phenyl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.