Description

4-Piperazin-1-Yl-2-(Trifluoromethyl)Pyrimidine CAS NO 503146-12-1 is a high-value, heterocyclic organic compound featuring a pyrimidine core substituted with a piperazine ring and a trifluoromethyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Chemical Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex molecular libraries due to its reactive piperazine nitrogen and pyrimidine ring.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers and advanced materials with unique properties.

Basic Information

Product Name	4-Piperazin-1-Yl-2-(Trifluoromethyl)Pyrimidine
CAS No.	503146-12-1
Molecular Formula	C9H11F3N4
Molecular Weight	232.21 g/mol
Synonyms	2-(Trifluoromethyl)-4-(1-piperazinyl)pyrimidine; 4-(Piperazin-1-yl)-2-(trifluoromethyl)pyrimidine; 2-Trifluoromethyl-4-piperazin-1-yl-pyrimidine; 1-[2-(Trifluoromethyl)pyrimidin-4-yl]piperazine; 4-(1-Piperazinyl)-2-(trifluoromethyl)pyrimidine; 503146-12-1; 4-Piperazin-1-yl-2-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Piperazin-1-Yl-2-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.