Description

2-Methanesulfonyl-Pyrimidine-4-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable pyrimidine derivative. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Chemical Synthesis: Versatile reagent for constructing pyrimidine-based heterocycles and introducing the methanesulfonyl and ester functional groups.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential compound for medicinal chemistry programs and discovery research in academic and CRO settings.

Basic Information

Product Name	2-Methanesulfonyl-Pyrimidine-4-Carboxylic Acid Ethyl Ester
CAS No.	503072-46-6
Molecular Formula	C9H12N2O4S
Molecular Weight	244.27 g/mol
Synonyms	Ethyl 2-(Methylsulfonyl)pyrimidine-4-carboxylate; 4-Pyrimidinecarboxylic acid, 2-(methylsulfonyl)-, ethyl ester; 2-Methylsulfonylpyrimidine-4-carboxylic acid ethyl ester; Ethyl 2-methanesulfonylpyrimidine-4-carboxylate; 2-Methanesulfonyl-4-pyrimidinecarboxylic Acid Ethyl Ester; 2-(Methylsulfonyl)-4-pyrimidinecarboxylic acid ethyl ester; CAS 503072-46-6
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonyl-Pyrimidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.