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3-Bromo-5-Fluoro-2-Methylaniline CAS NO 502496-36-8
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CAS No.:502496-36-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-5-Fluoro-2-Methylaniline is a halogenated aniline derivative, a versatile and high-value aromatic amine building block. This compound is critical for introducing specific bromo and fluoro substituents onto a methylated aniline core, enabling precise modulation of electronic and steric properties in target molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.
Application
- Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
- Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the specific halogen pattern enhances bioactivity.
- Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
- Dye and Pigment Intermediate: Employed in the creation of specialized halogenated dyes and colorants.
- Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
- Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.
Basic Information
| Product Name | 3-Bromo-5-Fluoro-2-Methylaniline |
| CAS No. | 502496-36-8 |
| Molecular Formula | C7H7BrFN |
| Molecular Weight | 204.04 g/mol |
| Synonyms | 2-Methyl-3-bromo-5-fluoroaniline; 3-Bromo-5-fluoro-2-methylbenzenamine; 2-Amino-6-bromo-4-fluorotoluene; Benzenamine, 3-bromo-5-fluoro-2-methyl-; 5-Fluoro-3-bromo-o-toluidine; 3-Bromo-5-fluoro-2-methyl-phenylamine; 6-Bromo-4-fluoro-2-methylaniline |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-5-Fluoro-2-Methylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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