Description

Methyl 5-Amino-2,6-Dichloropyrimidine-4-Carboxylate is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling the exploration of new chemical entities.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a building block in multi-step syntheses for final API production under GMP conditions where applicable.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized heterocyclic dyes and functional colorants.
• Material Science: Potential monomer or precursor for creating polymers and advanced materials with specific electronic or photonic properties.

Basic Information

Product Name	Methyl 5-Amino-2,6-Dichloropyrimidine-4-Carboxylate
CAS No.	502184-51-2
Molecular Formula	C7H6Cl2N3O2
Molecular Weight	235.05 g/mol
Synonyms	5-Amino-2,6-dichloropyrimidine-4-carboxylic acid methyl ester; Methyl 5-amino-2,6-dichloro-4-pyrimidinecarboxylate; 2,6-Dichloro-5-aminopyrimidine-4-carboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 5-amino-2,6-dichloro-, methyl ester; 5-Amino-2,6-dichloro-4-(methoxycarbonyl)pyrimidine
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2,6-Dichloropyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, providing full traceability and batch-to-batch consistency for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.