Description

4-(4-Boc-Piperazino-1-Yl)-3-Fluorophenol is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety and a fluorophenol group. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker component in the design of bifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Synthesis: Used in the construction of complex molecules designed to inhibit specific kinase enzymes involved in disease pathways.
• Chemical Biology Research: Employed as a tool compound for studying biological pathways and protein-ligand interactions.
• Process Chemistry & Scale-Up: Provides a reliable and scalable intermediate for transitioning from laboratory-scale research to commercial manufacturing.
• Custom Synthesis: Acts as a starting material for the custom synthesis of specialized compounds for preclinical and clinical studies.

Basic Information

Product Name	4-(4-Boc-Piperazino-1-Yl)-3-Fluorophenol
CAS No.	501126-38-1
Molecular Formula	C15H21FN2O3
Molecular Weight	296.34 g/mol
Synonyms	3-Fluoro-4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenol; 4-(4-Boc-Piperazin-1-yl)-3-fluorophenol; tert-Butyl 4-(5-fluoro-2-hydroxyphenyl)piperazine-1-carboxylate; 1-Boc-4-(5-fluoro-2-hydroxyphenyl)piperazine; 4-(N-Boc-piperazinyl)-3-fluorophenol; BOC-Piperazine-Fluorophenol Intermediate; 501126-38-1
EINECS	Contact for details

Quality Control

Our 4-(4-Boc-Piperazino-1-Yl)-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.