Description

Methyl 1,3-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidine-6-Carboxylate is a high-value, complex heterocyclic building block with the CAS registry number 501005-88-5. This compound serves as a critical advanced intermediate in the synthesis of novel pharmaceutical candidates, particularly those targeting complex biological pathways. It is primarily required by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process R&D for creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	Methyl 1,3-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	501005-88-5
Molecular Formula	C12H13N3O5
Molecular Weight	279.25 g/mol
Synonyms	Methyl 1,3-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydro-6H-pyrido[2,3-d]pyrimidine-6-carboxylate; 6H-Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 1,2,3,4,7,8-hexahydro-1,3-dimethyl-2,4,7-trioxo-, methyl ester; 1,3-Dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester; Pyrido[2,3-d]pyrimidine derivative; CAS 501005-88-5
EINECS	Contact for details

Quality Control

Our Methyl 1,3-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidine-6-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.